Infectious bronchitis virus initially infects and replicates in the upper‐respiratory tract causing the loss of protective cells lining the sinuses and trachea. After a brief viraemia, the virus can be detected in the kidneys, reproductive tract (Read more about variant D388 (QX)), and caecal tonsils.
Swollen pale kidneys in a chicken infected with IBV.
Some strains of IBV, which are referred to as nephropathogenic are known to cause lesions in the kidney. Renal damage associated with different IB strains is an increasingly important feature of IB infections, especially in broilers.